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Nucleolar DNA organization in the interphase nuclei of mouse fibroblasts.
Authors:M Pouchelet  A Anteunis  A Gansmüller  R E Robineaux
Abstract:The organization of nucleolar DNA in interphase nuclei of somatic cells was studied at the ultrastructural level using oxidized DAB as a nucleic acid stain. Some finely filamentous networks of DNA-containing structures were observed within the nucleolar fibrillar component. They originated from the perinucleolar shell of condensed chromatin and from a chromatinic area with a honeycomb like structure. The latter was significantly associated with nucleoli and is believed to be a part of the nucleolar organizer region.
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