Use of positron emission tomography to study tumors in vivo |
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| Institution: | 1. School of Computer Science, University of Sydney, NSW, Australia;2. Australian Research Council Training Centre for Innovative Bioengineering, NSW, Australia;3. Department of Molecular Imaging, Royal Prince Alfred Hospital, NSW, Australia;4. Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China;5. Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China;2. Department of Surgery, Skåne University Hospital, Malmö, Sweden;3. Department of Health Technology Assessment South, Skåne University Hospital, Lund, Sweden;4. Department of Radiation Physics, Skåne University Hospital, Malmö, Sweden;6. Department of Electrical Engineering, Chalmers University of Technology, Gothenburg, Sweden;5. Department of Clinical Physiology and Nuclear Medicine, Malmö Sweden;2. Department of Nuclear Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;3. Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland;4. Division of Molecular Imaging and Theranostics, Department of Nuclear Medicine, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria;6. Geneva University Neurocenter, Geneva University, Geneva, Switzerland;5. Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands |
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| Abstract: | Positron emission tomography (PET) is a non-invasive imaging technique. The ability of PET to visualize biochemistry and physiology in vivo distinguishes this technique from other imaging modalities and renders it of particular interest for oncological studies. PET studies can of en differentiate between normal and neoplastic tissue, as well as identify early signs of malignant degeneration through biochemical or physiological changes. Over the past several years, PET studies have been useful in the early diagnosis and the selection of treatment, as well as in following the progression or regression of malignant disease processes. Of particular significance, PET findings can be quantified by using mathematical modeling and computerized data analysis, which makes it possible to produce quantitative images of human pathophysiology in vivo. |
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