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心血管老化和心力衰竭
引用本文:陈磊,王跃群,吴秀山. 心血管老化和心力衰竭[J]. 生命科学研究, 2004, 0(Z1)
作者姓名:陈磊  王跃群  吴秀山
作者单位:湖南师范大学生命科学学院蛋白质化学与发育生物学教育部重点实验室 中国湖南长沙410081(陈磊,王跃群),湖南师范大学生命科学学院蛋白质化学与发育生物学教育部重点实验室 中国湖南长沙410081(吴秀山)
基金项目:国家自然科学基金项目(30170479,30270644,30213904),湖南省自然科学基金(02JJY4026,0355Y4011),教育部与湖南省教育厅基金(02A028,02B017,03C208)
摘    要:老年人心血管系统的老化是很明显的,动脉硬化改变了后负荷以及左心室的形状.尽管左心室的心脏收缩功能仍然能够维持,但是左心室的舒张功能则大大改变.运动时老年人的心血管功能产生明显的改变,老年人可以通过运动训练改善心血管功能.老化引起心血管结构和功能改变,从而降低心脏疾病出现的阈值.对老年人在运动或休息时心血管结构和功能的改变进行了综述.

关 键 词:老化  心血管功能  运动  心力衰竭

Cardiovascular Aging and Heart Failure
CHEN Lei,WANG Yue qun,WU Xiu shan. Cardiovascular Aging and Heart Failure[J]. Life Science Research, 2004, 0(Z1)
Authors:CHEN Lei  WANG Yue qun  WU Xiu shan
Abstract:The aging process is obvious in the cardiovascular system in older people. Stiffening of the arterial tree alters afterload and left ventricular geometry. Although resting left ventricular systolic function is maintained, left ventricular diastolic function changes substantially. Cardiovascular function in older people during exercise is also significantly altered but can be modified by exercise training in older adults. Age related changes in cardiovascular structure and function also lower the threshold at which cardiac diseases become apparent. The changes in cardiovascular structure and function at rest and during exercise in older people and highlights their consequences are reviewed.
Keywords:aging  cardiovascular function  exercise  heart failure
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