Synthesis of novel hydroxymethyl substituted analogues related to carbovir and neplanocin A |
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| Authors: | Franzyk Henrik Jensen Søren Rosendal Olsen Carl Erik Rasmussen Jon Holbech |
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| Affiliation: | Department of Organic Chemistry, Technical University of Denmark, Lyngby. |
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| Abstract: | Two enantiomerically pure hydroxymethyl substituted cyclopentene nucleoside analogues (42 and 53) related to carbovir and neplanocin A, respectively, were prepared from the chiral pool of iridoid glucosides. In addition two saturated hydroxymethylated analogues (44 and 45) were obtained from a protected intermediate. |
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