| 血清白细胞介素-18、氧化低密度脂蛋白与急性心肌梗死患者急诊PCI术后支架内再狭窄的关系 |
| |
| 引用本文： | 李猛,岳强,金慧. 血清白细胞介素-18、氧化低密度脂蛋白与急性心肌梗死患者急诊PCI术后支架内再狭窄的关系[J]. 现代生物医学进展, 2010, 10(24) |
| |
| 作者姓名： | 李猛 岳强 金慧 |
| |
| 作者单位： | 包头市中心医院心内科,内蒙古,包头,014040 |
| |
| 摘 要： | 目的:探讨血清白细胞介素-18(IL-18)、氧化低密度脂蛋白(ox-LDL)与急诊经皮冠状动脉介入治疗(PCI)术后支架内再狭窄的关系。方法:75例急性心梗急诊介入术后8～12个月内接受冠状动脉造影复查,其中9例有再狭窄作为再狭窄组,66例无再狭窄作为对照组。2组术后均接受阿司匹林、氯吡格雷、他汀类等药物治疗。取2组患者PCI术前、术后冠状动脉造影复查时血清标本,采用酶联免疫吸附法(EL ISA)检测血清IL-18、ox-LDL水平。结果:①再狭窄组PCI术后IL-18、ox-LDL水平较术前均明显升高[(2.37±0.22):(0.85±0.19)mg/L、(6.99±0.98):(2.38±1.06)mg/L],均P<0.01;对照组PCI后IL-18、ox-LDL水平较术前明显下降[(0.48±0.11):(1.23±0.09)mg/L、(1.39±0.54):(4.45±0.87)mg/L],P<0.05。②再狭窄组和对照组PCI术前IL-18、ox-LDL水平差异无统计学意义,再狭窄组PCI术后IL-18、ox-LDL水平显著高于对照组(均P<0.01)。④再狭窄组和对照组术前、术后IL-18和o...
|
| 关 键 词： | 急诊冠状动脉介入治疗 白细胞介素-18 氧化低密度脂蛋白 再狭窄 |
Relationship between plasma level of IL-18,ox-LDL and the development of emergency percutaneous coronary intervention |
| |
| LI Meng,YUE Qiang,JIN Hui. Relationship between plasma level of IL-18,ox-LDL and the development of emergency percutaneous coronary intervention[J]. Progress in Modern Biomedicine, 2010, 10(24) |
| |
| Authors: | LI Meng YUE Qiang JIN Hui |
| |
| Affiliation: | LI Meng,YUE Qiang,JIN Hui(Department of Cardiology,Baotou central Hospital,Baotou,014040,China) |
| |
| Abstract: | Objective: To investigate the relationship between serum level of interleukin-18,oxidized low density lipoprotein(ox-LDL) and the development of in stent restenosis after emergency percutaneous coronary intervention.Method: A total of seven-ty-five patients with successfully coronary stent implantation followed by coronary angiography within 8-12 months after emergency PCI were enrolled.patients with restenosis(n = 9) were assigned in restenosis group,and 66 patients in control group.Blood serum levels of I... |
| |
| Keywords: | emergency percutaneous coronary intervention interleukin-18 oxidized low-density lipoprotein coronary artery restenosis |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
