High-pressure liquid chromatography of neurotoxic phenylphosphonothioate esters and related compounds |
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| Authors: | J M Lasker K Sivarajah T E Eling M B Abou-Donia |
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| Affiliation: | 3M Company, 3M Center, Central Research Laboratories, St. Paul, Minnesota 55133 USA |
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| Abstract: | It has been suggested that perfluorooctanoic acid occurs in human plasma; however, no method of analysis for this compound in biological samples has been published to date. A method is presented for the analysis of perfluorooctanoic acid in plasma, urine, and liver tissue based on conversion of the acid to its methyl ester followed by separation and quantitation by gas chromatography. |
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| Keywords: | To whom reprint requests should be addressed. |
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