Spin trapping experiments with different carbamoyl-substituted EMPO derivatives |
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| Authors: | Stolze Klaus Rohr-Udilova Natascha Hofinger Andreas Rosenau Thomas |
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| Institution: | Molecular Pharmacology and Toxicology Unit, Department of Biomedical Sciences, University of Veterinary Medicine Vienna, Veterin?rplatz 1, A-1210 Vienna, Austria. Klaus.Stolze@vu-wien.ac.at |
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| Abstract: | The spin trapping behavior of five carbamoyl-substituted EMPO derivatives, 5-aminocarbonyl-5-methyl-pyrroline N-oxide (CAMPO (AMPO)), 5-aminocarbonyl-5-ethyl-pyrroline N-oxide (CAEPO), 5-aminocarbonyl-5-propyl-pyrroline N-oxide (CAPPO), 5-aminocarbonyl-5-n-butyl-pyrroline N-oxide (CABPO), and 5-aminocarbonyl-5-n-pentyl-pyrroline N-oxide (CAPtPO), toward different oxygen- and carbon-centered radicals is described, the stabilities of the superoxide adducts ranging from about 8 to 17min. |
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