Folding of peptide chains during formation of the spatial structure of protein molecules is determined by the code of amino acid codon roots]

Basing on the analysis of a large number of protein sequences (Cserzo M., Simon I., 1989), the structure of the amino acid nearest neighbour pair whose occurrence has a maximal positive deviation from the mean statistical value, is shown to correspond in most cases to the code of the amino acid codon roots. It reveals particularly amino acid pairs in n and n+5 positions of polypeptide chains. Amino acids belonging to A/U family contribute mostly to the folding of peptide chains.