| 长链非编码RNA与细胞多向分化 |
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| 引用本文： | 卢旱云,左长清,吴铁. 长链非编码RNA与细胞多向分化[J]. 中国生物化学与分子生物学报, 2014, 30(8): 746-751 |
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| 作者姓名： | 卢旱云 左长清 吴铁 |
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| 作者单位： | 广东医学院药理教研室, 广东 东莞523808 |
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| 基金项目： | 国家自然科学基金;东莞市高等院校科研机构科技项目 |
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| 摘 要： | 本文重点概述LncRNA参与细胞分化的相关机制,列举了LncRNA在不同细胞系中参与调控的各种作用方式,如LncRNA参与维持胚胎干细胞多潜能状态、胚胎干细胞分化、神经细胞分化、肌肉分化、表皮细胞分化、成骨细胞分化、脂肪生成的机制等.
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| 关 键 词： | 长链非编码RNA 细胞分化 机制 |
| 收稿时间： | 2013-12-30 |
Long Non-coding RNA and Cell Differentiation |
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| LU Han-Yun,ZUO Chang-Qing,WU Tie. Long Non-coding RNA and Cell Differentiation[J]. Chinese Journal of Biochemistry and Molecular Biology, 2014, 30(8): 746-751 |
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| Authors: | LU Han-Yun ZUO Chang-Qing WU Tie |
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| Affiliation: | Department of Pharmacology, Guangdong Medical College,
Dongguan523808, Guangdong, China |
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| Abstract: | In this paper, we reviewed the diverse mechanisms that long non-coding RNA(LncRNA) regulated cell differentiation via several representative differentiation systems, such as the mechanism that LncRNA maintains the pluripotent state of embryonic stem cells and regulates stem cells differentiation, neural cell differentiation, muscle differentiation, epidermal differentiation, osteoblast differentiation and adipogenesis. |
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| Keywords: | long non-coding RNA cell differentiation mechanism |
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