Protein-lipoprotein interactions in the haemolymph of Locusta during the action of adipokinetic hormone: The role of CL-proteins |
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Authors: | Colin H. Wheeler Graham J. Goldsworthy |
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Affiliation: | Department of Zoology, University of Hull, North Humberside, HU6 7RX, U.K. |
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Abstract: | The involvement of CL-proteins in the formation of lipoprotein A+ during adipokinetic hormone action has been investigated using radiolabelling experiments. Injected [3H]-CL-proteins associate rapidly with lipoprotein A+ during its formation. Both [3H]-CL-proteins and [3H]-Ayellow are liberated from [3H]-A+ during its natural degradation in the haemolymph (when adipokinetic hormone action is declining). It appears that [3H]-CL-proteins bind reversibly to A+, since they are easily displaced in vivo and in vitro by competing concentrations of non-labelled CL-proteins. It is suggested that Ayellow is an integral component of the A+ lipoprotein complex, whereas CL-proteins may play only a relatively minor part in its structural organisation. Possible functions of the binding of CL-proteins to A+ are discussed. |
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