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The amino acid sequence of the C- terminal cyanogen bromide peptide of human J chain
Authors:J E Mole  A S Bhown  J C Bennett
Institution:1. Division of Clinical Immunology and Rheumatology Department of Medicine University of Alabama in Birmingham Birmingham, Alabama 35294 USA;2. Department of Microbiology University of Alabama in Birmingham Birmingham, Alabama 35294 USA
Abstract:The carboxyl-terminal peptide obtained from human J chain treated with cyanogen bromide (CNBr)1 has been isolated and the amino acid sequence determined as Val - Glx - Thr - Ala - Leu - Thr - Pro - Asx - Ala - CMCys - Tyr - Pro - Asx. Comparisons with the primary structures of human lambda, kappa, alpha, or mu chains failed to disclose analogous regions with these immunoglobulins.
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