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Structural investigation of a water-soluble glucan from an edible mushroom, Astraeus hygrometricus
Authors:Chakraborty Indranil  Mondal Soumitra  Pramanik Malay  Rout Dilip  Islam Syed S
Affiliation:Department of Chemistry & Chemical Technology, Vidyasagar University, West-Midnapore 721 102, West Bengal, India.
Abstract:A water-soluble glucan, Fraction I, was isolated from the aqueous extract of the fruit bodies of the mushroom Astraeus hygrometricus. On the basis of total hydrolysis, methylation analysis, periodate oxidation, and NMR studies ((1)H, (13)C, 2D-COSY, TOCSY, NOESY, and HSQC), the structure of the repeating unit of the glucan is determined as:This glucan shows strong splenocyte activation.
Keywords:Astraeus hygrometricus   Ectomycorrhiza   Polysaccharide   Structure   NMR spectroscopy   Splenocyte activation
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