Extracts and sesquiterpene derivatives from the red alga Laurencia chondrioides with antibacterial activity against fish and human pathogenic bacteria |
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Authors: | Bansemir Anne Just Natalie Michalik Manfred Lindequist Ulrike Lalk Michael |
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Institution: | Institute of Pharmacy, Department of Pharmaceutical Biology, Ernst-Moritz-Arndt University of Greifswald, Jahnstrasse 17, D-17487 Greifswald. |
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Abstract: | During screening of seaweeds from different places in Europe for antimicrobial activities against human and fish pathogenic bacteria, Laurencia chondrioides was identified as a promising species. By bioassay-guided isolation, followed by structure elucidation by mass spectrometry and 1H- and 13C-NMR spectrometry, two sesquiterpenoides of the chamigrene-type from the selected red seaweed Laurencia chondrioides were identified. Both compounds inhibit the growth of some fish and human pathogenic bacteria. |
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