Intracellular motility: myosin and tropomyosin in actin cable flow |
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| Authors: | Kovar David R |
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| Institution: | Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA. drkovar@uchicago.edu |
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| Abstract: | A new study has found that retrograde flow of budding yeast actin cables is facilitated by myosin II but is inhibited by a specific tropomyosin isoform (Tpm2p). Budding yeast therefore contains a minimal component system for elucidating the mechanistic details of retrograde actin flow. |
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