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Electron microscopy of beef heart mitochondrial F1-ATPase
Authors:V L Tsuprun  I V Mesyanzhinova  I A Kozlov  E V Orlova
Affiliation:1. A.V. Shubnikov Institute of Crystallography, USSR Academy of Sciences, Moscow 117333 USSR;2. A.N. Belozersky Laboratory of Molecular and Bioorganic Chemistry, Moscow State University, Moscow 117234, USSR
Abstract:The quaternary structure of isolated and membrane-bound F1-ATPase (submitochondrial particles) has been studied by electron microscopy. A model of the molecule has been proposed: six protein masses are arranged in two layers approximately at the vertices of a triangular antiprism. Computer averaging of the images showed that the frontal view of the molecule can be approximately characterized by mirror plane symmetry.
Keywords:Enzyme structure  Electron microscopy
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