Non-conventional hosts for the production of fuels and chemicals |
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| Institution: | 1. Department of Food Science and Technology, University of California Davis, One Shields Ave, Davis, CA 95616, USA;2. Forestry Research and Development Agency (FORDA), the Ministry of Forestry, Jalan Gunung Batu No. 5, Bogor 16610, Indonesia;3. Department of Biosystems Engineering, University of Manitoba, Winnipeg, MB R3T 2 N2, Canada;4. Department of Viticulture and Enology, University of California Davis, One Shields Ave, Davis, CA 95616, USA;5. Department of Chemical Engineering and Materials Science, University of California Davis, One Shields Ave, Davis, CA 95616, USA |
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| Abstract: | Biotechnology offers a green alternative for the production of fuels and chemicals using microbes. Although traditional model hosts such as Escherichia coli and Saccharomyces cerevisiae have been widely studied and used, they may not be the best hosts for industrial application. In this review, we explore recent advances in the use of nonconventional hosts for the production of a variety of fuel, cosmetics, perfumes, food, and pharmaceuticals. Specifically, we highlight twenty-seven popular molecules with a special focus on recent progress and metabolic engineering strategies to enable improved production of fuels and chemicals. These examples demonstrate the promise of nonconventional host engineering. |
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| Keywords: | Non-conventional hosts Fuels Chemicals Metabolite building-blocks |
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