Cryptic variants of acrocentric human chromosomes as analysed by restriction endonucleases |
| |
Authors: | S. F. De Cabo P. Ludeña M. Velázquez C. Sentis J. Fernández-Piqueras |
| |
Affiliation: | (1) Departamento de Biología, Unidad de Genética, Módulo C-XV, Facultad de Ciencias, Universidad Autónoma de Madrid, 28049 Madrid, Spain |
| |
Abstract: | Ten phenotypically normal human individuals have been analysed by in situ treatments with restriction endonucleases in order to obtain a better characterization of some cryptic variants of acrocentric chromosomes. Treatments with AluI, NdeII and Sau 3AI confirm the existence of two cryptic amplified regions on the short arms of both one chromosome 15 and one chromosome 22, in one female. These amplifications seem to be of different origin involving the nucleolar organizer region of chromosome 15 and the satellite of chromosome 22. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|