首页 | 本学科首页   官方微博 | 高级检索  
     

丝状真菌的细胞凋亡
引用本文:厉晓东,卢建平,李海娇,林福呈. 丝状真菌的细胞凋亡[J]. 微生物学通报, 2011, 38(2): 242-249
作者姓名:厉晓东  卢建平  李海娇  林福呈
作者单位:1. 浙江大学生命科学学院,浙江,杭州,310058
2. 浙江大学生物技术研究所,浙江,杭州,310058
基金项目:国家自然科学基金项目(No. 30971879)
摘    要:凋亡是一种程序性细胞死亡类型,为多细胞生物发育和维持生命所必需的,也普遍存在于细菌等原核生物和酵母、丝状真菌等真核生物中。丝状真菌既具有酵母和哺乳动物共有的凋亡同源蛋白,也具有酵母所不具备的哺乳动物凋亡同源蛋白,所以其凋亡机制较酵母更为复杂,而又较哺乳动物简单。凋亡在丝状真菌的发育、繁殖、衰老等过程中具有重要的作用。近年,丝状真菌作为新的凋亡研究的模式生物被广泛研究,而且进展迅速。综述丝状真菌的凋亡现象和检测方法,丝状真菌中凋亡的生物学功能,丝状真菌凋亡的诱导条件,以及丝状真菌凋亡相关基因的功能研究进展。

关 键 词:凋亡  丝状真菌  凋亡基因  综述
收稿时间:2010-08-30
修稿时间:2010-11-22

Apoptosis in filamentous fungi
LI Xiao-Dong,LU Jian-Ping,LI Hai-Jiao and LIN Fu-Cheng. Apoptosis in filamentous fungi[J]. Microbiology China, 2011, 38(2): 242-249
Authors:LI Xiao-Dong  LU Jian-Ping  LI Hai-Jiao  LIN Fu-Cheng
Affiliation:School of Life Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China;School of Life Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China;Institute of Biological Technologies, Zhejiang University, Hangzhou, Zhejiang 310058, China;Institute of Biological Technologies, Zhejiang University, Hangzhou, Zhejiang 310058, China
Abstract:Apoptosis is an important type of programmed cell death, which is necessary for the development and growth of higher eukaryotes including bacteria, yeast and filamentous fungi. It has been found that the apoptotic mechanism in filamentous fungi is more complex compared to yeast as they contain several homologs of the mammalian apoptosis-regulated proteins which are not present in the yeast genome. Apoptosis plays important roles in the development, reproduction and aging of filamentous fungi. Today, as new model organisms for apoptotic research, the filamentous fungi have been widely studied. In this paper we reviewed the phenomena, detection methods, functions and induction mechanisms of apoptosis in filamentous fungi.
Keywords:Apoptosis   Filamentous fungi   Apoptotic protein   Review
本文献已被 CNKI 万方数据 等数据库收录!
点击此处可从《微生物学通报》浏览原始摘要信息
点击此处可从《微生物学通报》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号