The cytogenetics of mutator gene-induced X-linked lethals in Drosophila melanogaster |
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Authors: | M M Green G Lefevre |
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Institution: | 1. Department of Genetics, University of California, Davis, Calif. 95616, USA;2. Department of Biology, California State University, Northridge, Calif. 91324 U.S.A. |
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Abstract: | A third chromosome mutator gene effectively increases the spontaneous frequency of sex-linked recessive lethals in females but not in females of Drosophila melanogaster. Approximately half the mutator-induced mutants occur as clusters of the same mutant implying a premeiotic origin. An appreciable number of the mutator-induced lethals are associated with comparatively long deficiencies of several salivary gland chromosome bands. The possible modes of mutator gene action are conjectured. |
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