首页 | 本学科首页   官方微博 | 高级检索  
     


Localization and detection of ovarian follicular fluid protein in follicles of human ovaries.
Authors:T D Nandedkar  J K Shahid  R Mehta  S B Moodbidri  U C Hegde  I N Hinduja
Affiliation:Institute for Research in Reproduction (Indian Council of Medical Research), Bombay.
Abstract:Human ovarian follicular fluid protein has been partially purified and the active fraction designated as hGF2. Using specific polyclonal antiserum to hGF2, it was observed to be localized immunohistochemically in the granulosa cells of medium but not large follicles of human ovary. The hGF2 levels were estimated by ELISA in serum and follicular fluid of 10 gonadotropin-stimulated women recruited for IVF-ET programme. The results revealed a 3-fold increase in the concentration of hGF2 in follicular fluid compared to that in serum of these patients. These data indicate that the protein is secreted by granulosa cells and plays an important role in the regulation of follicular maturation and ovulation.
Keywords:
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号