Bacterial DNA segregation by the actin-like MreB protein |
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Authors: | Kruse Thomas Gerdes Kenn |
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Affiliation: | Department of Biochemistry and Molecular Biology, Campusvej 55, University of Southern Denmark, DK-5230 Odense M, Denmark. |
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Abstract: | Faithful chromosome segregation is vital to all organisms. Eukaryotic cells use the tubulin-based cytoskeleton to segregate their chromosomes during mitosis. A handful of papers have provided convincing evidence that, in bacteria, this task is accomplished by the actin homolog MreB. In particular, a recent study by Gitai et al. demonstrates that MreB specifically binds to and segregates the replication origin of the bacterial chromosome. |
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