布比卡因与左旋布比卡因在剖宫产手术中麻醉效果比较*

摘要目的：探讨蛛网膜下腔注射左旋布比卡因和布比卡因对剖宫产手术中的麻醉效果。方法：选取2012 年3 月到2013 年3 月 期间在我院住院进行剖宫产手术产妇60 例作为研究对象。随机分为左旋布比卡因组与布比卡因组，观察两组患者的麻醉效果以 及术后不良反应的发生情况。结果：剖宫产手术中左旋布比卡因和布比卡因的蛛网膜下腔注射麻醉后的5 min 和7 min 后MAP 值与麻醉前比较差异具有统计学意义（P<0.05）。左旋布比卡因和布比卡因的蛛网膜下腔注射麻醉后的5 min、7 min、10 min 以及 15minHR值比较差异具有统计学意义（P<0.05）。左旋布比卡因和布比卡因的蛛网膜下腔注射麻醉后Bromage 评分0分时间和麻 醉后切口感觉疼痛时间相比差异具有统计学意义（P<0.05）。左旋布比卡因和布比卡因麻醉后的不良反应的发生率比较差异无统 计学意义（P>0.05）。结论：剖宫产手术麻醉中布比卡因的麻醉效果好于左旋布比卡因，临床上剖宫产等腹部手术应该选择布比卡 因进行临床麻醉。

Comparative Analysis on the Anesthetic Effects of Bupivacaine and Levobupivacaine Subarachnoid Injections during Cesarean SectionOperation*

ABSTRACT Objective:To observe and compare the anesthesia effects of bupivacaine and levobupivacaine subarachnoid injections during the operation of cesarean section.Methods: Sixty cases of parturients who underwent cesarean section operation in the hospital between March 2012 and March 2013 were selected as study objects. They were randomly divided into levobupivacaine and bupivacaine group. The former received intrathecal levobupivacaine for preoperative anesthesia, and the latter was given subarachnoid injection of bupivacaine anesthesia before the operation. Observations were made to both groups in terms of the anesthesia effects and the occurrence of postoperative adverse reactions.Results: After bupivacaine and levobupivacaine subarachnoid injections for anesthesia, the MAP values of 5 min and 7 min during cesarean section operation were of statistically significant difference when compared with that before anesthesia(P<0.05). There were statistically significant differences between HR values of 5min, 7min, 10min and 15min after bupivacaine and levobupivacaine subarachnoid injection (P<0.05), so were the differences between the Bromage scores of 0 min and the time of feeling the incision pain (P<0.05). However, there were no significant difference in the incidence of postoperative adverse reactions between levobupivacaine group and bupivacaine group were much the same (P>0.05). Conclusion:The bupivacaine had better anesthetic effect than levobupivacaine in cesarean section operation.