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Effect of copper on inhibition by nitrapyrin of growth ofNitrosomonas europaea
Authors:Dr Steven J Powell  James I Prosser
Institution:(1) Department of Microbiology, University of Aberdeen, Marischal College, AB9 1AS Aberdeen, Scotland;(2) Present address: Process Development Department, Beecham Pharmaceuticals UK Division, Clarendon Road, BN14 8QH Worthing, Sussex, UK
Abstract:Exponentially growing cultures ofNitrosomonas europaea were inhibited by addition of 0.5 mgrg nitrapyrin ml–1. This inhibition was increased by simultaneous addition of 0.046 mgrg Cu2+ ml–1 as copper sulfate. This contradicts a previous report that copper relieves inhibition of ammonia oxidation by nitrapyrin, which report has formed the basis for hypotheses regarding the mechanism of action of this inhibitor.
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