Ontogeny of hematological cell and biochemical profiles in maternal and fetal baboons (Papio species) |
| |
Authors: | Schlabritz-Loutsevitch Natalia E Hubbard Gene B Jenkins Susan L Martin Helen C Snider Cathy S Frost Patrice A Michelle Leland M Havill Lorena M McDonald Thomas J Nathanielsz Peter W |
| |
Affiliation: | Southwest National Primate Research Center, Southwest Foundation for Biomedical Research, San Antonio, TX 78227-5301, USA. nschlabr@icarus.sfbr.org |
| |
Abstract: | The normal ranges of hematological cell profiles and biochemistry are documented in adult non-pregnant, pregnant, juvenile, and neonatal baboons. Despite the extensive use of the baboon as a model for the study of various aspects of pregnancy, there is no data from paired mothers and their fetuses at different stages of gestation. Hematologic and biochemical profile data were obtained from eight non-pregnant female baboons, 37 mothers and 38 fetal baboons at 30 +/- 2, 90 +/- 2, 125 +/- 2, and 175 +/- 2 days of gestation (mean +/- range; dGA; term, 180 dGA). Changes observed in fetal and maternal blood during normal baboon pregnancy were similar to those reported in human pregnancy. The level of alkaline phosphatase was two times higher in fetal blood circulation than that reported in human pregnancy. |
| |
Keywords: | blood biochemistry blood hematology nonhuman primates pregnancy |
本文献已被 PubMed 等数据库收录! |
|