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Localization of neutral Mn-dependent DNAse in rat hepatocytes. An immunofluorescent study |
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| Authors: | Z I Abramova N L Zotkina M M Belova N G Khamidullina V G Vinter |
| Abstract: | Rabbit antibodies against the Mn-dependent DNAse were obtained. The specificity of the anti-DNAse antibody was established by the enzyme inhibition in vitro. The enzyme activity was inhibited by more than 75 and 54% using rabbit antisera and affinity-purified IgG. Localization of the enzyme in the rat hepatocyte nuclei was studied by indirect immunofluorescence. |
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