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Mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex |
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| Authors: | Marcus S. Dyer Laura A. Reale Katherine E. Lewis Adam K. Walker Tracey C. Dickson Adele Woodhouse Catherine A. Blizzard |
| Affiliation: | 1. Menzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, Tas, Australia;2. Neurodegeneration Pathobiology Laboratory, Queensland Brain Institute, University of Queensland, Brisbane, Qld, Australia;3. Wicking Dementia Research and Education Centre, College of Health and Medicine, University of Tasmania, Hobart, Tas, Australia |
| Abstract: | |
| Keywords: | ALS cortex excitability glutamate hyperexcitability mislocalisation mouse model TDP-43 |