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Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing |
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| Authors: | Tatsuya Manabe Ildikó Rácz Stephanie Schwartz Linda Oberle Francesco Santarelli Julius V Emmrich Jonas J Neher Michael T Heneka |
| Institution: | 1. Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany;2. Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany
German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany;3. Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany;4. German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany;5. Department of Neurology and Department of Experimental Neurology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany;6. Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany |
| Abstract: | |
| Keywords: | complement hippocampus Sepsis-associated encephalopathy synapse synaptic pruning |