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Plasma metabolites associated with biomarker evidence of neurodegeneration in cognitively normal older adults |
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| Authors: | Pratishtha Chatterjee Yeo-Jin Cheong Atul Bhatnagar Kathryn Goozee Yunqi Wu Matthew McKay Ian J. Martins Wei L. F. Lim Steve Pedrini Michelle Tegg Victor L. Villemagne Prita R. Asih Preeti Dave Tejal M. Shah Cintia B. Dias Stephanie J. Fuller Heidi Hillebrandt Sunil Gupta Eugene Hone Kevin Taddei Henrik Zetterberg Kaj Blennow Hamid R. Sohrabi Ralph N. Martins |
| Affiliation: | 1. Department of Biomedical Sciences, Macquarie University, North Ryde, NSW, Australia;2. Department of Molecular Sciences, Macquarie University, North Ryde, NSW, Australia;3. Department of Biomedical Sciences, Macquarie University, North Ryde, NSW, Australia KaRa Institute of Neurological Disease, Sydney, NSW, Australia Clinical Research Department, Anglicare, Sydney, NSW, Australia School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, WA, Australia;4. School of Medical and Health Sciences, Edith Cowan University, Patricia Sarich Neuroscience Research Institute, Nedlands, WA, Australia;5. The Florey Institute of Neuroscience and Mental Health, University of Melbourne, VA, Australia;6. Department of Biomedical Sciences, Macquarie University, North Ryde, NSW, Australia Clinical Research Department, Anglicare, Sydney, NSW, Australia;7. Department of Biomedical Sciences, Macquarie University, North Ryde, NSW, Australia School of Medical and Health Sciences, Edith Cowan University, Patricia Sarich Neuroscience Research Institute, Nedlands, WA, Australia Australian Alzheimer’s Research Foundation, Nedlands, WA, Australia;8. School of Medical and Health Sciences, Edith Cowan University, Patricia Sarich Neuroscience Research Institute, Nedlands, WA, Australia Australian Alzheimer’s Research Foundation, Nedlands, WA, Australia;9. Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Mölndal, Sweden Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK UK Dementia Research Institute at UCL, London, UK;10. Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Mölndal, Sweden Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden;11. Department of Biomedical Sciences, Macquarie University, North Ryde, NSW, Australia School of Medical and Health Sciences, Edith Cowan University, Patricia Sarich Neuroscience Research Institute, Nedlands, WA, Australia Australian Alzheimer’s Research Foundation, Nedlands, WA, Australia Centre for Healthy Ageing, School of Psychology and Exercise Science, College of Science, Health, Engineering and Education, Murdoch University, Murdoch, WA, Australia;12. Department of Biomedical Sciences, Macquarie University, North Ryde, NSW, Australia School of Medical and Health Sciences, Edith Cowan University, Patricia Sarich Neuroscience Research Institute, Nedlands, WA, Australia KaRa Institute of Neurological Disease, Sydney, NSW, Australia School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, WA, Australia Australian Alzheimer’s Research Foundation, Nedlands, WA, Australia |
| Abstract: | |
| Keywords: | Alzheimer's disease biomarkers metabolomics neurodegeneration neurofilament light preclinical Alzheimer's disease |