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Pre- and early postnatal enriched environmental experiences prevent neonatal hypoxia-ischemia late neurodegeneration via metabolic and neuroplastic mechanisms |
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| Authors: | Luz Elena Durán-Carabali Felipe Kawa Odorcyk Samuel Greggio Gianina Teribele Venturin Eduardo Farias Sanches Guilherme Garcia Schu Andrey Soares Carvalho Thales Avila Pedroso Natividade de Sá Couto-Pereira Jaderson Costa Da Costa Carla Dalmaz Eduardo Rigon Zimmer Carlos Alexandre Netto |
| Institution: | 1. Graduate Program in Biological Sciences: Physiology, Instituto de Ciências Básicas da Saúde (ICBS), Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil;2. Preclinical Research Center, Brain Institute (BraIns) of Rio Grande do Sul, Porto Alegre, Brazil;3. Graduate Program in Biological Sciences: Biochemistry, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil;4. Graduate Program in Biological Sciences: Neuroscience, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil;5. Department of Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil;6. Graduate Program in Biological Sciences: Biochemistry, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Graduate Program in Biological Sciences: Neuroscience, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil Department of Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil;7. Graduate Program in Biological Sciences: Pharmacology and Therapeutics, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil Department of Pharmacology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil |
| Abstract: | |
| Keywords: | [18F]-FDG microPET APP brain development brain metabolism cognitive impairment Environmental enrichment GAP-43 |