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PEAR1 is a potential regulator of early hematopoiesis of human pluripotent stem cells |
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| Authors: | Shuo Zhang Kengyuan Qu Shuzhen Lyu Dixie L Hoyle Cory Smith Linzhao Cheng Tao Cheng Jun Shen Zack Z Wang |
| Institution: | 1. State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China
Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China;2. State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China Department of Histology and Embryology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China;3. State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China;4. Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;5. Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China;6. State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, Tianjin, China Department of Stem Cell & Regenerative Medicine, Peking Union Medical College, Tianjin, China |
| Abstract: | |
| Keywords: | endothelial-to-hematopoietic transition (EHT) hematopoietic development hemogenic endothelium (HE) human pluripotent stem cells (hPSCs) platelet endothelial aggregation receptor-1 (PEAR1) |