The effectiveness of phototherapy for surface decontamination against SARS-Cov-2. A systematic review |
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| Authors: | Susyane Vieira de Oliveira Filipe Danilo das Neves Daniela Carvalho dos Santos Mariana Bernardes Batista Monteiro Maristela S. Spanghero Beatriz Nascimento Motta Igor Pereira de Oliveira Maria Fernanda Setúbal Destro Rodrigues Adriana Lino dos Santos Franco Rebeca Boltes Cecatto |
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| Affiliation: | 1. Biophotonics Applied to Health Sciences Postgraduate Program, Nove de Julho University / Universidade Nove de Julho / UNINOVE, Sao Paulo, Brazil School of Medicine, Nove de Julho University / Universidade Nove de Julho / UNINOVE, Sao Paulo, Brazil;2. School of Medicine, Nove de Julho University / Universidade Nove de Julho / UNINOVE, Sao Paulo, Brazil;3. Biophotonics Applied to Health Sciences Postgraduate Program, Nove de Julho University / Universidade Nove de Julho / UNINOVE, Sao Paulo, Brazil |
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| Abstract: | COVID-19 appeared in December 2019, needing efforts of science. Besides, a range of light therapies (photodynamic therapy, ultraviolet [UV], laser) has shown scientific alternatives to conventional decontamination therapies. Investigating the efficacy of light-based therapies for environment decontamination against SARS-CoV2, a PRISMA systematic review of Phototherapies against SARS-CoV or MERS-CoV species discussing changes in viral RT-PCR was done. After searching MEDLINE/PubMed, EMBASE, and Literatura Latino-Americana e do Caribe em Ciências da Saúde we have found studies about cell cultures irradiation (18), blood components irradiation (10), N95 masks decontamination (03), inanimate surface decontamination (03), aerosols decontamination (03), hospital rooms irradiation (01) with PDT, LED, and UV therapy. The best quality results showed an effective low time and dose UV irradiation for environments and inanimate surfaces without human persons as long as the devices have safety elements dependent on the surfaces, viral charge, humidity, radiant exposure. To interpersonal contamination in humans, PDT or LED therapy seems very promising and are encouraged. |
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| Keywords: | COVID-19 decontamination photobiomodulation phototherapy SARS-CoV-2 |
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