Genotoxicity of polycyclic aromatic hydrocarbons in Escherichia coli PQ37. |
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| Authors: | V Mersch-Sundermann S Mochayedi S Kevekordes |
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| Institution: | Institute of Medical Microbiology and Hygiene, Faculty of Clinical Medicine Mannheim, University of Heidelberg, F.R.G. |
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| Abstract: | In the present investigation, 32 polycyclic aromatic hydrocarbons (PAHs) were tested for genotoxicity in E. coli PQ37 using the standard tube assay of the SOS chromotest. PAHs such as benzoghi]fluoranthene, benzoj]fluoranthene, benzoa]pyrene, chrysene, dibenzoa,l]pyrene, fluoranthene and triphenylene exhibited high genotoxicity when incubated in the presence of an exogenous metabolic activation mixture. The results were compared to those obtained with the Salmonella/microsome test. |
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