A method for the determination of hyaluronate in the presence of other glycosaminoglycans and its application to human intervertebral disc. |
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Authors: | T E Hardingham and P Adams |
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Abstract: | A highly sensitive proteoglycan-binding assay was developed for the detection and determination of small amounts of hyaluronate. Application of this assay to human intervertebral-disc tissue showed that the radial distribution of hyaluronate closely followed the distribution of proteoglycans. |
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