Factors affecting mito-nuclear codon usage interactions in the OXPHOS system of Drosophila melanogaster

Codon usage bias varies considerably among genomes and even within the genes of the same genome.In eukaryotic organisms,energy production in the form of oxidative phosphorylation(OXPHOS) is the only process under control of both nuclear and mitochondrial ge-nomes.Although factors affecting codon usage in a single genome have been studied,this has not occurred when both interactional ge-nomes are involved.Consequently,we investigated whether or not other factors influence codon usage of coevolved genes.We us...