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Medium-term outcomes of 78,808 patients after heart valve surgery in a middle-income country: a nationwide population-based study
Authors:Regina Maria de Aquino Xavier  Vitor Manuel Pereira Azevedo  Paulo Henrique Godoy  Arn Migowski  Antonio Luiz Pinho Ribeiro  Rogério Brant Martins Chaves  Marcelo Goulart Correia  Carolina de Aquino Xavier  Lucas de Aquino Hashimoto  Clara Weksler  Nelson Albuquerque Souza e Silva
Affiliation:1.Hospital School, National Institute of Cardiology (INC), Ministry of Health,Rio de Janeiro,Brazil;2.Hospital Naval Marcílio Dias,Rio de Janeiro,Brazil;3.University Hospital and School of Medicine - Universidade Federal de Minas Gerais (UFMG),Minas Gerais,Brazil;4.University Hospital and School of Medicine, Federal University of Rio de Janeiro (UFRJ),Rio de Janeiro,Brazil;5.Hospital Municipal Salgado Filho,Rio de Janeiro,Brazil
Abstract:

Background

Heart valve surgery outcomes are unknown in middle-income countries and thus cannot be used in health system decision making processes. This study estimated in-hospital mortality and medium and long-term survival.

Methods

This was a retrospective study of 78,806 patients who underwent heart valve surgery between 2001 and 2007 in Brazil. Two national databases were used, the Hospital Information System and the Mortality Information System. Kaplan-Meier survival analysis and log-rank tests were performed. Maximum and median follow-up was 7.7 and 2.8 years, respectively (0.002–7.707).

Results

Valve replacement accounted for 69.1% of procedures performed. Mitral stenosis, the most common valve injury, represented 38.9% of the total. In 94.7% of mitral stenosis patients, aetiology was rheumatic heart disease. In-hospital mortality was 7.6% and was higher for women, for patients who had undergone concomitant coronary artery bypass grafting (CABG) and for the elderly. Overall survival was 69.9% at the end of follow-up. Survival was worst among elderly, male and concomitant CABG patients (P<0.001).

Conclusions

Rheumatic heart disease is still a major public health problem in Brazil. In-hospital mortality and global survival rates of patients who have undergone heart valve surgery were less satisfactory than those reported in high-income countries. The findings of this study can contribute to guiding decision making processes in middle-income countries similar to Brazil and others concerned with improving the quality of care.
Keywords:
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