| The Alb3/Oxa1/YidC protein family: membrane-localized chaperones facilitating membrane protein insertion? |
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| 作者姓名： | Kuhn A Stuart R Henry R Dalbey RE |
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| 摘 要： |
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The Alb3/Oxa1/YidC protein family: membrane-localized chaperones facilitating membrane protein insertion? |
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| Kuhn A,Stuart R,Henry R,Dalbey RE.The Alb3/Oxa1/YidC protein family: membrane-localized chaperones facilitating membrane protein insertion?[J].Trends in Cell Biology,2003,13(10):510-516. |
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| Authors: | Kuhn Andreas Stuart Rosemary Henry Ralph Dalbey Ross E |
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| Institution: | Institute of Microbiology and Molecular Biology, University of Hohenheim, 70599 Stuttgart, Germany. andikuhn@uni-hohenheim.de |
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| Abstract: | The recently identified Alb3/Oxa1/YidC family constitutes a novel class of proteins that function in promoting membrane insertion in chloroplasts, mitochondria and bacteria. These proteins mediate membrane insertion of a diverse group of membrane proteins that range from phage coat proteins in bacteria and respiratory-chain protein subunits in mitochondria to the light-harvesting chlorophyll-binding proteins in chloroplasts. Here, we discuss the Alb3/Oxa1/YidC protein family and their possible function as membrane chaperones, helping newly synthesized proteins to fold into the membrane bilayer. |
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