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Prostaglandin treatment is associated with a withdrawal of progesterone and androgen at the receptor level in the uterine cervix
Authors:Ylva Vladic-Stjernholm  Tomislav Vladic  Chellakkan S Blesson  Gunvor Ekman-Ordeberg  Lena Sahlin
Affiliation:(1) Division for Obstetrics and Gynecology, Department of Women's and Children's Health, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden;(2) Division for Reproductive Endocrinology, Department of Women's and Children's Health, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden
Abstract:Treatment with prostaglandin(PG)-E2 is clinically efficient for cervical priming. The aim of this study was to evaluate the impact of PG-E2 on the expression of the progesterone (PR), androgen (AR) and glucocorticoid (GR) receptors in human uterine cervix in prolonged pregnancy.
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