Effect of depletion of glutathione by buthionine sulfoximine on lipid peroxidation in rats acutely treated with ethanol |
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| Affiliation: | 1. Psychology Department, Northwestern University, United States;2. Spatial Intelligence and Learning Center, Northwestern University, United States;1. Universidade Federal de Santa Catarina, Florianópolis, Brazil;2. Departamento de Ingeniería de Sistemas y Automática, Universidad de Sevilla, Sevilla, Spain;1. Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA;2. Scripps Research Institute, Jupiter, FL 33458, USA;3. Wakayama Medical University, 811-1 Kimiidera, Wakayama 641-8509, Japan;1. Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain;2. Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain;3. Hospital 12 de Octubre, Madrid, Spain;4. Hospital Universitario de Álava, Vitoria-Gasteiz, Álava, Spain;5. Departamento de Preventiva y Salud Publica, Facultad de Medicina, Universidad de Cantabria, Santander, Cantabria, Spain |
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| Abstract: | - 1.1. The effect of depletion of glutathione (GSH) by dl-buthionine-S,R-sulfoximine (BSO) on lipid peroxidation in rats acutely treated with ethanol was investigated.
- 2.2. BSO pretreatment has not been found to potentiate an increase in liver, brain and erythrocyte lipid peroxide levels.
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