多分DNA病毒及其在寄生蜂与寄主关系中的作用

分DNA病毒(PDV)在协调寄生蜂与寄主的相互关系中起重要作用。该文就PDV 的特征、PDV与寄生蜂的相互关系、PDV对鳞翅目寄主的免疫抑制及发育调节等方面进行综述。

Polydnavirus and its functions in parasitoid-host interactions

Polydnaviruses (PDV) are symbiotic viruses of certain parasitic Hymenoptera, and have been found only in Ichneumonidae and Braconidae. These viruses are assigned to the family Polydnaviridae which consists of two groups, ichnovirus and bracovirus. Polydnavirus genome is made up of multiple superhelical closed circles of double\|stranded DNA. Viral replication is restricted to the calyx epithelial cells of parasitoid ovary, and the PDV can be transmitted vertically in the form of an endogenous provirus during parasitization. These viruses can inhibit the host immunosystem, which allows the parasitiod to develop in host without encapsulation and melanization, and modifies the physiology, growth and development of their hosts. The influences of polydnavirus on host immunity and endocrinology have attracted much academic attention in the last decade. Detailed research progress on polydnaviruses and their functions as mutualists and pathogens is reviewed.