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The effect of different genetic properties of Salmonella typhimurium on the determination of stabilities and mutagenic concentrations of chemical carcinogens using the diffusion bioassay
Authors:T E Awerbuch  A J Sinskey
Abstract:The mutagenic sensitivity of SV50, the R-factor plasmid containing tester, of the Salmonella/arabinose-resistant assay system has been evaluated with different environmental complex mixtures, including extracts of airborne and diesel emission particles, oil-shale ash, nitrosated coal dust and water samples. The mutagenicities of all extracts were detectable with this assay. This study indicates that the arabinose-resistant assay with SV50 is useful for the detection of the mutagenic activity of environmental complex mixtures.
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