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Isolation of scopoletin from leaves of Hevea brasiliensis and the effect of scopoletin on pathogens of H. brasiliensis
Authors:Silva  W P K  Deraniyagala  S A  Wijesundera  R L C  Karunanayake  E H  Priyanka  U M S
Institution:(1) Department of Plant Pathology, Rubber Research Institute, Dartonfield, Agalawatta, Sri Lanka;(2) Department of Chemistry, University of Colombo, Colombo 3, Sri Lanka;(3) Department of Botany, University of Colombo, Colombo 3, Sri Lanka;(4) Department of Biochemistry & Molecular Biology, Faculty of Medicine, University of Colombo, Colombo 8, Sri Lanka
Abstract:Scopoletin (7-hydroxy-6-methoxy coumarin) which inhibited the conidial germinationof Corynespora cassiicola was isolated from the uninfected mature leaves ofHevea brasiliensis. Scopoletin was not detected in uninfected immature rubber leaves. The immature leaves produced scopoletin after being infected with C. cassiicola. The concentration of scopoletin in infected leaves was higher than in uninfected mature leaves. Scopoletin also inhibited the conidial germination of other fungal pathogens of H. brasiliensis. However, no correlation was observed between scopoletin accumulation and clonal resistance. This revised version was published online in June 2006 with corrections to the Cover Date.
Keywords:anti-fungal compounds            Corynespora cassiicola
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