Heat inactivation of tissue thromboplastin]

Molecular mechanism of thermal inactivation of thromboplastin from the human brain using 1H, 31P-NMR has been studied. It was concluded that heating causes denaturation of protein moiety, disturbs hexagonal (H11) form of packing, immobilizes the lipids and decreases the mobility of their molecular segments. The dynamic properties of lipids become more homogeneous.