On a simple way to verify the experimental agreement of any two-state mathematical model of muscle contraction

In the usual theories of muscular contraction, the crossbridges are considered to be the force generators leading to the sliding of the thick and the thin filaments past each other. The first mathematical treatment of such models was that of Huxley (1957) and since this date the formalism has been continuously improved. Here we have obtained a relation identifiable to the mathematical expression of the Fenn effect. This relation leads to a new expression of the tension P(V), which must be compared with that directly obtained from mechanical considerations. These two expressions do not fit in the currently accepted two-state models.