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Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset
Authors:Sung E Choe  Michael Boutros  Alan M Michelson  George M Church and Marc S Halfon
Institution:(1) Department of Genetics, Harvard Medical School, New Research Building, 77 Avenue Louis Pasteur, Boston, MA 02115, USA;(2) Division of Genetics, Department of Medicine, Brigham and Women's Hospital, New Research Building, 77 Avenue Louis Pasteur, Boston, MA 02115, USA;(3) Howard Hughes Medical Institute, Brigham and Women's Hospital, 20 Shattuck Street, Boston, MA 02115, USA;(4) Department of Biochemistry, 140 Farber Hall, 3435 Main St., SUNY at Buffalo, Buffalo, NY 14214, USA;(5) Center of Excellence in Bioinformatics, 140 Farber Hall, 3435 Main St., SUNY at Buffalo, Buffalo, NY 14214, USA;(6) German Cancer Research Center (DKFZ/B110), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany
Abstract:

Background  

As more methods are developed to analyze RNA-profiling data, assessing their performance using control datasets becomes increasingly important.
Keywords:
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