The gene for human growth hormone-releasing factor (GHRF) maps to or near chromosome 20p12. |
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Authors: | V V Rao C L?ffler S Schnittger I Hansmann |
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Affiliation: | Institut für Humangenetik, Universit?t G?ttingen, Germany. |
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Abstract: | Growth hormone-releasing factor (GHRF), a hypothalamic releasing factor also named somatocrinin, influences the secretion and synthesis of growth hormone. Human GHRF is encoded by a single gene which was assigned to chromosome 20 by dot-blot analysis of DNA from dual laser sorted chromosomes. Using a radioactive cDNA probe, we localized the GHRF gene to chromosome 20p12 or near band 20p12. |
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