Nonsensitized lymphocytes produce leukocyte interferon when cultured with foreign cells. |
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Authors: | J E Blalock M P Langford J Georgiades G J Stanton |
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Institution: | Department of Microbiology, University of Texas Medical Branch, Galveston, Texas 77550 U.S.A. |
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Abstract: | Nonsensitized human lymphocytes produce interferon when cultured with either transformed or normal heterologous cells. De novo RNA and protein synthesis was not required in a foreign cell for it to act as the inducer. The interferon produced has been characterized as being leukocyte type rather than immune or fibroblast type. |
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