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Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ |
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| Authors: | James E. Brownell Michael D. Sintchak James M. Gavin Hua Liao Frank J. Bruzzese Nancy J. Bump Teresa A. Soucy Michael A. Milhollen Xiaofeng Yang Anne L. Burkhardt Jingya Ma Huay-Keng Loke Trupti Lingaraj Dongyun Wu Kristin B. Hamman James J. Spelman Courtney A. Cullis Steven P. Langston Stepan Vyskocil Todd B. Sells Lawrence R. Dick |
| Affiliation: | 1. Discovery, Millennium Pharmaceuticals, Inc., 40 Landsdowne Street, Cambridge, MA 02139, USA |
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