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Repetitive domain of Clostridium difficile toxin B exhibits cytotoxic effects on human intestinal epithelial cells and decreases epithelial barrier function
Authors:Mateja Zemljic  Maja Rupnik  Melania Scarpa  Gregor Anderluh  Gorgio Palù  Ignazio Castagliuolo
Affiliation:1. Institute of Public Health Maribor, Centre for Microbiology, Research Department, Maribor, Slovenia;2. University of Maribor, Faculty of Medicine, Maribor, Slovenia;3. University of Padua, Department of Histology, Microbiology and Medical Biotechnologies, Padua, Italy;4. University of Ljubljana, Biotechnical Faculty, Ljubljana, Slovenia;1. ICS-6 Strukturbiochemie, Forschungszentrum Jülich, 52425 Jülich, Germany;2. Institut für Physikalische Biologie, Heinrich-Heine-Universität, 40225 Düsseldorf, Germany;1. Institut für Experimentelle und Klinische Pharmakologie und Toxikologie der Albert-Ludwigs-Universität Freiburg, Albert-Str. 25, 79104 Freiburg, Germany;2. Centre for Biological Signalling Studies (BIOSS), Germany;1. Department of Environmental and Biological Sciences and Technologies, University of Salento, Lecce, Italy;2. Biological Medical Center “Tecnomed”, Nardò, Lecce, Italy;1. Laboratory of Cellular and Molecular Neurobiology, Department of Pathology and Experimental Therapeutics, Campus of Bellvitge, University of Barcelona, Hospitalet de Llobregat, Barcelona, 08907, Spain;2. Biomedical Research Institute of Bellvitge (IDIBELL), Hospitalet de Llobregat, Barcelona, 08907, Spain;3. Institut de Neurociències, Universitat de Barcelona, Barcelona 08035, Spain;1. Department of Neurological Surgery, Juntendo University Urayasu Hospital, Japan;2. Department of Neurological Surgery, Juntendo University School of Medicine, Japan
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