Conserved features of cohesin binding along fission yeast chromosomes |
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| Authors: | Christine K Schmidt Neil Brookes Frank Uhlmann |
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| Affiliation: | (1) Chromosome Segregation Laboratory, Cancer Research UK London Research Institute, Lincoln's Inn Fields, London, WC2A 3PX, UK;(2) Bioinformatics and Biostatistics Service, Cancer Research UK London Research Institute, Lincoln's Inn Fields, London, WC2A 3PX, UK;(3) National Cancer Institute, NIH, Bethesda, MD 20892, USA;(4) Trinity Centre for High Performance Computing, Trinity College, Dublin 2, Ireland |
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| Abstract: | Background Cohesin holds sister chromatids together to enable their accurate segregation in mitosis. How, and where, cohesin binds to chromosomes are still poorly understood, and recent genome-wide surveys have revealed an apparent disparity between its chromosomal association patterns in different organisms. |
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