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Inhibition of RANKL‐dependent cellular fusion in pre‐osteoclasts by amiloride and a NHE10‐specific monoclonal antibody
Authors:Yuichi Mine  Takahiro Shuto  Hiroki Nikawa  Toshihisa Kawai  Masaru Ohara  Kazuko Kawahara  Kouji Ohta  Toshio Kukita  Yoshihiro Terada  Seicho Makihira
Affiliation:1. Department of Oral Biology and Engineering, Integrated Health Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan;2. Section of Fixed Prosthodontics, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka, Japan;3. Department of Immunology and Infectious Diseases, The Forsyth Institute, Cambridge, MA, USA;4. Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA;5. Hiroshima University Hospital, Dental Clinic, Higashihiroshima, Japan;6. Department of Molecular Cell Biology and Oral Anatomy, Faculty of Dental Science, Kyushu University, Fukuoka, Japan
Abstract:
Keywords:amiloride  cell–  cell fusion  monoclonal antibody  NHE10  osteoclast  RANKL
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